GLP-1 Medications (Ozempic, Wegovy, Mounjaro) and Surgery
What are GLP-1 medications?
Medicines such as Ozempic, Wegovy, and Mounjaro are used to help manage diabetes and weight loss.
They may also be known as:
- Semaglutide
- Tirzepatide
- Dulaglutide
- Liraglutide
- Exenatide
- Lixisenatide
These medications work by mimicking natural hormones that help regulate appetite and slow stomach emptying.
Why does this matter for surgery?
Because GLP-1 medications slow stomach emptying, they can affect:
- Fasting requirements
- Anaesthesia
- Surgical planning
In rare cases, they may increase certain risks around the time of surgery.
What should you do?
If you are taking a GLP-1 medication and are planning to have surgery, please inform:
- Your pre-assessment team
- Your anaesthetist
- Your surgeon
This information is important for your safety.
Will I need to stop my medication?
Not always.
Decisions about continuing or temporarily stopping your medication are made using shared decision-making between you and your clinical team.
Your doctors will consider:
- Your procedure
- Your medical condition
- Your blood sugar control
Stopping GLP-1 medication may increase blood sugar levels, which can also affect surgical risk. For this reason, plans are made individually.
Current guidance
With appropriate assessment and planning, GLP-1 medications do not automatically need to be stopped before surgery
- Clear communication with your healthcare team allows safe planning and reduces risk.
- Always follow the advice provided by your anaesthetist or surgeon.
- If you have concerns about your medication, please speak with your clinical team.