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Each breast cancer is unique. Breast cancer typing can identify the differences between tumours, allowing The London Clinic to offer our patients customised care.  All therapies have side-effects, so it’s important to avoid unnecessary treatments. Breast cancer typing can help us work out which tumour is more likely to spread and which women may get the most benefit from further treatments like chemotherapy.

Techniques for the diagnosis, assessment and treatment of breast cancer have become more sophisticated. The London Clinic offers special tests to look at groups of genes in the tumours. Breast cancer typing or Gene Expression Profiling (GEP) can predict how likely a particular cancer is to grow and spread, enabling our consultants to plan the very best treatment for each individual cancer.

The London Clinic offers investigations and tests for breast cancer in a private, comfortable and stress-free environment. Our world-leading specialists will provide you with the information and support you need to fully understand the tests and the implications of the results.

Why choose The London Clinic?

The London Clinic is dedicated to providing the best, personalised healthcare with over 600 world-renowned consultants available to offer informed health advice and treatment. There are no waiting lists; screening tests and investigations can be arranged at a time to suit you.

Spanning Harley Street and Devonshire Place, The London Clinic is situated in the heart of London’s internationally-known medical district. This central location, together with state-of-the art technologies and facilities not widely available in other hospitals, makes The London Clinic the hospital of choice for around 120,000 patients every year.

Offering affordable and competitive self-pay packages and expert support from Clinical Nurse Specialists and specialised multidisciplinary teams, 98% of our patients said they would recommend The London Clinic to their friends and families.

Understanding your investigation

Gene Expression Profiling is a method of looking at cancer cells and analysing the activity of certain genes. This can help predict the behaviour of the cancer, including the likelihood that it will grow rapidly and spread to other parts of the body.

The tests can be done on core-biopsies, which are performed under local-anaesthetic in the clinic. However, they are often carried out on sections from the tumour, after it has been removed. This allows your consultant to plan whether any further treatment after surgery would be valuable.

It is important to understand that Gene Expression Profiling is not the same as genetic testing. Genetic testing focuses on conditions that run in some families. For breast cancer, this involves looking for the faulty genes BRCA1 and BRCA2, which may be linked to cancer in around 1 in 20 women.

Breast cancer typing facts

The London Clinic offers two of the latest methods of breast cancer typing:

EndoPredict® 

The EndoPredict test looks at the activity of eight different genes within a tumour sample. The test then uses the information, alongside the size of the tumour and their nodal status (whether or not the cancer has spread to the lymph nodes) to give a score estimating the risk of the breast cancer spreading to other organs - where it becomes incurable – in the next ten years.

Oncotype DX®

The Oncotype DX test looks at 21 genes within the cancer cells, it is usually used in the assessment of intermediate cancers. It is carried out on the cancer after it has been removed by your surgeon. The sample is sent to a dedicated laboratory in the USA, for specialist analysis. A Recurrence Score is calculated, and given as a number between 0 and 100. A high number indicates a greater risk of the disease returning1.

Breast cancer typing results

The results of breast cancer typing are sent to your specialist within 10–14 days. You will be given an appointment to discuss the results. At this stage, your consultant will explain the findings of the analysis and the implications for your health. A treatment programme can then be planned, always bearing in mind your feelings, opinions and general health.

Breast cancer typing costs

Cancer care at The London Clinic may be covered by your insurance. We also offer affordable, competitive self-pay packages for cancer tests and treatment. Please call +44 (0) 207 616 7693 to speak to our helpful team and find out more about breast cancer typing and to book an appointment.

[1] Breast cancer typing

Appointment enquiries: +44 (0) 20 3944 1073 Concierge service: +44 (0) 203 219 3323 Self-Pay service: +44 (0) 203 918 7301International office: +44 (0) 203 219 3266 Invoice and payment enquiries: +44 (0) 207 616 7708 General enquiries: +44 (0) 20 3918 9135

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