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The London Clinic
Dr Matt Williams specialises in the treatment of brain tumours, including benign and malignant tumours and brain metastases. He has expanded the use of a second course of radiotherapy (re-irradiation), particularly in combination with chemotherapy. He is one of the few clinicians in the UK to have experience across the range of all three stereotactic platforms (LINAC, CyberKnife and GammaKnife) for delivering highly focused radiotherapy. At The London Clinic he chairs the brain tumour (neuro-oncology) MDT.

Specialties and sub-specialties

Brain tumour chemotherapy
Brain tumour radiotherapy
Brain metastases
Recurrent Glioma
Stereotactic radiotherapy


Professional profile

Dr Matthew Williams trained in Birmingham, before moving to London where he trained at the Hammersmith Hospital. 

He completed his clinical oncology training in London, followed by a PhD with the Advanced Computation Lab at CRUK/UCL. He was appointed as a consultant at Imperial College Healthcare NHS Trust in February 2012, where he specialises in neuro-oncology and is joint MDT lead for neuro-oncology.

He is an Honorary Senior Fellow at Imperial College, where he leads the Computational Oncology Group. He sits on the NCRI Brain Tumour clinical trials group, and has a particular interest in studies looking at novel approaches to improving current treatments in neuro-oncology.
He chairs the neuro-oncology MDT at The London Clinic, and has worked to make The London Clinic the only site in the UK that offers the INTRAGO-II trial of intra-operative radiotherapy in newly diagnosed patients with GBM

Clinical interests

  • Radiotherapy-chemotherapy combinations for glioma
  • Metabolic approaches to modulating radiotherapy response in glioma
  • Computational Oncology

Current posts

  • Consultant Clinical Oncologist
    Imperial College Healthcare NHS Trust
  • Honorary Senior Fellow
    Imperial College

Current teaching posts

  • Honorary Senior Research Fellow
    Imperial College London

Medical training

Year qualified 1999
  • Birmingham 1999


Launch of landmark clinical trial for brain cancer treatment
The London Clinic
The London Clinic is the first and only UK hospital to participate in a landmark international phase 3 clinical trial of a treatment called intraoperative radiotherapy (IORT) for glioblastoma multiforme, a brain cancer with a high mortality rate.