London Clinic Lung Centre

Early stage lung cancer

Also known as: Stage 1 or 2 lung cancer, Localised lung cancer, Curable lung cancer

Lung cancer is one of the most common cancers in the UK. Globally, lung cancer is the leading cause of cancer-related deaths, so receiving an early diagnosis and prompt treatment is vital.

Only a small proportion of lung cancer cases are detected in its earliest stage. At The London Clinic Lung Centre, we offer expert-led early diagnosis and treatment.

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What is early stage lung cancer?

Lung cancer typically develops in your airways or lung tissue, but it can remain asymptomatic (cause no symptoms) until it reaches more advanced stages. Early stage lung cancer is when lung cancer develops in your lung tissue but hasn’t spread to other body parts.

Early detection of lung cancer is critical, so being aware of possible symptoms means you can access treatment sooner rather than later – potentially saving your life.

Early lung cancer symptoms

Early stage lung cancer does not always cause symptoms. However, as it becomes more advanced, it can cause symptoms like:

  • A persistent cough that doesn’t go away or gets worse over time – could signal irritation or an obstruction in your airways
  • Shortness of breath, particularly during physical activity – this can suggest tumour growth
  • Chest pain especially when coughing, laughing or breathing deeply – could indicate problems with your lungs or chest wall
  • Unexplained fatigue – could be a result of your body’s response to cancer or decreased oxygen levels
  • Unintentional weight loss – may be a sign of cancer affecting your metabolism
  • Coughing up blood (haemoptysis) – you should never ignore even small amounts of blood as it could suggest damage to your airways
  • Hoarseness – changes to your voice may be due to tumours pressing on the nerves controlling your vocal cords

Early lung cancer diagnosis

Several investigations can help diagnose lung cancer. First, it’s vital to have an initial specialist consultation with a member of our team. We’ll assess your symptoms, medical history and risk factors in detail to determine if you need any further diagnostic tests.

The next step is imaging tests, which can include:

We’ll sometimes take a lung biopsy (tissue sample), too. The three types of biopsy are:

  • Imaging–guided biopsy – we collect tissue samples using a CT or ultrasound scan to guide us in locating the tumour
  • Endoscopy techniques – we use a bronchoscopy or endobronchial ultrasound to sample tissue from your airways or lymph nodes
  • Video-assisted thoracoscopy – we use minimally invasive techniques to capture images of your lungs and collect biopsies

We may suggest molecular profiling, where we check the tumour to identify genetic mutations or markers that can help guide us when deciding on targeted therapies or immunotherapy treatments.

Our multidisciplinary team of oncologists, surgeons, radiologists and pathologists will review our findings carefully to provide an accurate diagnosis and a personalised treatment strategy tailored to your needs.

What causes early stage lung cancer?

The cause of lung cancer is abnormal cells in your lungs growing out of control. The reasons why cancer cells develop can vary, but smoking is the leading cause. Tobacco contains carcinogens (a substance that can cause cancer) and damages your lungs progressively.

Other causes of lung cancer can include:

  • Secondhand smoke – exposure to smoke from others increases your lung cancer risk, even if you don’t smoke
  • Radon gas – this naturally occurring radioactive gas can be present in homes and workplaces, increasing your risk of lung cancer
  • Asbestos exposure – asbestos is a natural mineral, but its fibres settle in your lungs and can lead to mesothelioma (cancer of the pleura). It’s typically found in occupational settings
  • Air pollution – exposure to pollutants in the air increases your lung cancer risk
  • Genetics – a family history of lung cancer can elevate your risk of lung cancer
  • Radiation therapy – previous radiation therapy on your chest can increase your risk of lung cancer

Who is most at risk?

Some age groups and genders may have a higher risk of developing lung cancer. Generally, it’s more common in those over 50, with the risk significantly increasing in those over 65. Historically, lung cancer was more prevalent in men, but the rates of disease in women have been climbing.

Different lifestyle factors can also affect your risk of lung cancer, some of which are preventable. Smoking is the most common but also the most preventable.

Poor diet and lack of exercise may also contribute to an increased lung cancer risk, as it can cause a weakened general wellbeing.

If you’re worried about your risk of lung cancer, then attending early lung cancer screenings and awareness of the symptoms can help improve your treatment outcome.

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When to see a consultant?

You should see a lung expert if you have symptoms of early-stage lung cancer or consider a low-dose CT scan (LDCT) for screening if you:

  • 50–80 years old
  • have a history of heavy smoking (at least 20 pack-years)
  • currently smoke or have quit within the past 15 years
  • are in good health

Early detection means you can receive treatment as soon as possible, improving your chances of a complete recovery.

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Early lung cancer treatment

Treating lung cancer is most effective in its early stages, and we offer various treatment options.

Surgery is typically recommended for early-stage lung cancer. Our expert surgeons perform lobectomies to remove the affected lung lobe, or sometimes a segmentectomy/wedge resection to remove a smaller portion. Surgery offers the best chance of cure when the cancer is confined to the lungs.

Additional therapies, such as immunotherapy, chemotherapy, or targeted treatments, may be used before or after surgery to eliminate remaining cancer cells. Radiation therapy may be an alternative if surgery isn’t possible.

If the cancer has spread to nearby tissue or lymph nodes, we may combine chemotherapy and radiation to shrink tumours and prevent progression. Modern treatments like Durvalumab (immunotherapy) or Osimertinib (a third-generation EGFR inhibitor) can also help prevent recurrence after surgery or radiotherapy.

Why patients choose The London Clinic Lung Centre

Why patients choose The London Clinic Lung Centre

Our lung centre brings together a wide range of specialities and collective experience to provide a comprehensive approach to diagnosing and treating lung conditions. Working collaboratively, our world-class teams deliver personalised care at every stage, ensuring each patient receives the highest standard of treatment in a supportive, streamlined environment.

World-class lung treatment

Our specialists work at the forefront of modern lung diagnostics and treatments, helping deliver exceptional care for chest conditions.

Personal care, every time

Patient care is central to everything we do, with tailored treatment plans and support at every step.

Effortlessly simple

Our multidisciplinary teams work as one to provide a seamless, stress-free experience from consultation to follow-up.

Get expert lung advice

World-class consultants and advanced lung diagnostics, based in the heart of Harley Street.

Frequently asked questions (FAQs)

Get answers to questions you may have about accessing world-class treatment at The London Clinic Lung Centre.