London Clinic Lung Centre

Small cell lung cancer

Also known as: SCLC, Oat cell carcinoma, Oat cell cancer

Small cell lung cancer (SCLC) is a rare, fast-growing cancer that requires immediate treatment. However, most cases of small cell lung cancer are not diagnosed until the condition has reached an advanced stage.

At The London Clinic Lung Centre, we provide rapid diagnosis and advanced treatment options that can transform your prognosis.

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What is small cell lung cancer?

Small cell lung cancer occurs when healthy cells in the lungs become cancerous and begin to multiply quickly. Clumps of these cancerous cells can form masses (tumours) in the lungs, which may then spread through the bloodstream to other parts of the body – including the liver, brain and bones.

There are two main subtypes of small cell lung cancer:

  • Small cell carcinoma – the most common form
  • Combined small cell carcinoma – a rarer type, made up of a combination of small cell and non-small cell lung cancer cells

Because this type of lung cancer can spread so quickly, early diagnosis is imperative for positive treatment outcomes.

Small cell lung cancer symptoms

In its early stages, small cell lung cancer rarely causes noticeable symptoms. When symptoms do appear, they are often very similar to those of other types of lung cancer.

Common symptoms include:

  • A cough that seems to be getting worse
  • Coughing up blood (haemoptysis)
  • Chest pain or discomfort
  • Pain in the bones (which may indicate that the cancer has spread)
  • Difficulty breathing or shortness of breath
  • Swelling in the face or neck veins
  • Unexplained weight loss
  • Fatigue (constant tiredness)
  • Hoarseness in your voice when speaking
  • Difficulty swallowing (dysphagia)
  • Wheezing
  • Headaches, dizziness and confusion

It is important to note that these symptoms are common across different types of lung cancer and other conditions, so they do not necessarily indicate small cell lung cancer.

Small cell lung cancer diagnosis

If it is diagnosed early, small cell lung cancer is typically identified through low-dose CT screening. This type of scan uses a much lower dose of radiation than a standard CT scan, meaning it can be performed regularly if you have a high risk of lung cancer – for example, if you have a history of smoking.

If you have not been diagnosed using a low-dose CT and you are experiencing symptoms of small cell lung cancer, your specialist may recommend one or more of the following tests:

  • Chest X-ray – often the first port of call to check for any abnormal masses or spots in your lungs
  • Positron emission tomography (PET) or CT scans – when performed together, these scans can help identify where a tumour is, its size and if it has spread
  • An endobronchial ultrasound (EBUS) – a minimally invasive procedure which uses ultrasound technology to view your lungs in real-time and collect tissue samples (biopsy) for further testing
  • Rapid molecular diagnostics – using next-generation sequencing (NGS) to provide a full picture of your tumour’s genetic profile, helping to guide diagnosis and a tailored treatment plan

No matter the stage of your condition, our multidisciplinary team of specialists will carefully review the findings to create a personalised treatment plan that’s built around your unique needs.

What causes small cell lung cancer?

While small cell lung cancer can affect anyone, it occurs most commonly in people who have smoked, currently smoke or have been exposed to second-hand tobacco smoke.

That said, other factors can increase the risk of developing small cell lung cancer, including:

  • A family history of lung cancer – there is a genetic component to certain types of lung cancer
  • Exposure to carcinogens in a workplace – including asbestos, tar, nickel or arsenic
  • Air pollution – such as long-term exposure to fine particulate matter
  • Radiation – from cancer screening scans or treatments which use radiation
  • Exposure to radon gas – a colourless, odourless gas that naturally comes up from rocks and soil
  • Having a weakened immune system – for example, due to conditions that suppress your immune system
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When to see a consultant?

Experiencing symptoms of small cell lung cancer may indicate that the cancer has spread to other parts of your body, which is why it is important to seek medical care as soon as possible.

However, you may be able to identify small cell lung cancer before symptoms develop. Regular lung cancer screening can help identify small cell lung cancer in its early stages. Screening is particularly recommended if you have a history of smoking.

At The London Clinic Lung Centre, we offer a low-dose computed tomography (CT) scan screening service to enable early detection and peace of mind.

Why patients choose The London Clinic Lung Centre

Why patients choose The London Clinic Lung Centre

Our lung centre brings together a wide range of specialities and collective experience to provide a comprehensive approach to diagnosing and treating lung conditions. Working collaboratively, our world-class teams deliver personalised care at every stage, ensuring each patient receives the highest standard of treatment in a supportive, streamlined environment.

World-class lung treatment

Our specialists work at the forefront of modern lung diagnostics and treatments, helping deliver exceptional care for chest conditions.

Personal care, every time

Patient care is central to everything we do, with tailored treatment plans and support at every step.

Effortlessly simple

Our multidisciplinary teams work as one to provide a seamless, stress-free experience from consultation to follow-up.

Get expert lung advice

World-class consultants and advanced lung diagnostics, based in the heart of Harley Street.

Frequently asked questions (FAQs)

Get answers to questions you may have about accessing world-class treatment at The London Clinic Lung Centre.

There are a few key differences between small cell lung cancer and non-small cell lung cancer:

  • Growth rate – small cell lung cancer tends to spread more quickly than non-small cell lung cancer
  • Location – while small cell lung cancer typically develops in one type of cell in one area of the lungs, non-small cell lung cancer can affect up to three different types of cells and may appear in different areas of your body, including the lungs
  • Frequency – small cell lung cancer is less common, accounting for around 15% of all lung cancer cases, whereas non-small cell lung cancer makes up approximately 85% of cases
  • Size – as their names suggest, small cell lung cancer cells are much smaller than non-small cell lung cancer cells