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Capsule endoscopy

The London Clinic has introduced a successful GI capsule endoscopy service to the existing gastrointestinal services. The first capsule endoscopy at The London Clinic was performed in May 2006, and patient referrals continue to increase.  Capsule endoscopy allows clinicians to fully investigate and treat patients with known or suspected gastrointestinal disorders, particularly conditions that may affect the small bowel.

 

Description

Complete endoscopic examination of the small intestine has not been possible until now. Capsule endoscopy provides excellent visualisation of the entire small intestine using a pill-sized, video imaging, wireless capsule that is swallowed by the patient. Each capsule contains a camera, light-emitting diodes, batteries and a transmitter.

 

During the procedure the patient can move freely around, and over 50,000 colour images are recorded onto a data-recorder worn on a belt around the patient’s waist. The capsule passes through the small intestine as peristalsis occurs and is excreted naturally by the patient.

Endocapsule

 

Each capsule contains:

- a camera

- light-emitting diodes

- batteries

- a radio-transmitter

        The Olympus EndoCapsule

 

 

 

 

        

 

Benefits of capsule endoscopy

 

Holding Capsule White

Capsule endoscopy has many benefits:

 

- the capsule is small and easily swallowed

- it is painless and sedation free during the procedure 

- the patient can relax in comfort and walk about

- exposure to potentially harmful radiation does

  not occur

- additional investigations can often be avoided

- patients go home later the same day

 

 

 

Key findings of multiple clinical trials show that capsule endoscopy is significantly superior for examination of the small intestine for a broad range of indications compared to:

 

- small bowel enteroclysis

- barium follow-through

- CT and MRI

- push enteroscopy

- ileoscopy

Small Intestine
  Capsule view of small intestine

 

Indications for capsule endoscopy

The main indications for capsule endoscopy include:

 

- iron deficiency anaemia when obscure gastrointestinal bleeding is suspected

- diagnosis of early or suspected small bowel Crohn’s disease

- detection of benign and malignant small intestinal tumours (e.g. polyps, GISTs, lymphoma)

   evaluation of Coeliac disease (not responding to treatment or where there is doubt about 

   the diagnosis) and other other malabsorption disorders that may lead to chronic diarrhoea

   and weight loss

- identification of medication related to small bowel injury (e.g. NSAID-induced enteropathy) 

- an additional diagnostic facility for possible small bowel abnormalities identified by other

  investigations (such as CT, MRI or barium X-rays) requiring further investigation

 

Investigations normally performed prior to capsule endoscopy

Generally patients will have undergone a gastroscopy and colonoscopy prior to capsule endoscopy, as many conditions commonly affect the stomach and colon. If these prove unhelpful then a capsule endoscopy may be considered.

 

Should the patient’s symptoms include significant abdominal pain, distension and/or vomiting, it may be necessary to arrange a Patency Capsule or a barium small bowel examination before capsule endoscopy to exclude possible obstruction.

 

Contra-indications for capsule endoscopy

Capsule endoscopy is contra-indicated in patients:

 

- with known or suspected gastrointestinal obstruction, strictures, or fistulas

- when swallowing disorders are present (although the capsule can be placed endoscopically)

- during pregnancy

 

The capsule may be used in patients with cardiac pacemakers and other implanted

electro-medical devices; however, temporary cardiac monitoring may be required.

 

Side effects

Capsule endoscopy is a well-tolerated and safe procedure and side effects are rare. To date, more than 400,000 examinations have been performed worldwide. The main risk is capsule retention, which is estimated to occur in fewer than 0.75% of cases. In the rare instances when this occurs, an endoscopy or an operation may be required to remove the capsule.

 

Should there be any doubts about using the capsule, a biodegradable Patency Capsule (which dissolves away should it get stuck) or a barium small bowel examination may be performed first.

 

Preparing for capsule endoscopy

Capsule endoscopy is patient friendly and preparation usually involves dietary modification only. Unlike conventional endoscopy, no sedation or analgesia is necessary.  Patients can

have a room at the Clinic reserved for their use during the test, but are still able to go home later the same day.

 

Preparation for capsule endoscopy is simple:

 

- On the day before the procedure, lunch is followed by clear fluids and then an overnight fast.

- The capsule is swallowed by the patient with some water in the morning on the day of the 

  procedure.

- Fluids may be taken after two hours and a snack after four hours.

- Patients taking iron tablets will need to stop these for one week beforehand

 

The capsule endoscopy nurse will ensure that patients are fully informed in advance of the procedure.  Special arrangements will be organised if patients are diabetic or have a cardiac pacemaker.

 

Information written by Dr Chris Fraser, MB ChB MD MRCP (Consultant Gastroenterologist and Specialist Endoscopist)

 

Our experts

 

Capsule Endoscopy Nurse

 

See our capsule endoscopy consultants

 

Michelle McCabe

 

Contact details

 

 

 

 

Telephone

 

Fax

Endoscopy Unit

The London Clinic

20 Devonshire Place

London W1G 6BW

 

020 7616 7760

 

020 7616 7684

 

 


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