Show telephone contact numbers
Hide telephone contact numbers
General enquiries:
Book an appointment:
Self-pay enquiry:
The London Clinic
Dr Alastair O'Brien is a Consultant Hepatologist at The London Clinic, specialising in liver conditions.

Make an appointment

Fast track your treatment with Dr Alastair O'Brien. Call us on 020 3944 1073.

Book appointment now

Specialties and sub-specialties


Specialist microsite

London Liver Group

Professional profile

Dr Alastair O’Brien is a Clinical Senior Lecturer and Consultant Hepatologist at University College London and The Royal Free Hospitals. His research in infection and liver disease has been published in the most prestigious medical Journals such as The Lancet, Nature Medicine, Hepatology and Gastroenterology.
He currently holds approximately £2million in grant funding from the Wellcome Trust, The Medical Research Council and The Department of Health. He is able to combine clinical excellence with running a laboratory research group and a clinical trial team. He is the chief investigator for ATTIRE which will be the largest interventional study ever performed in patients with acute decompensation of cirrhosis taking place at more than 20 sites over the next three years.
He is also the associate editor for the British Medical Journal open Gastroenterology and has written the hepatology chapter for the best-selling medical textbook Kumar and Clarke’s Clinical Medicine, 9th Edition.
Dr O’Brien is a great advocate of patient choice and believes that empathy and listening to people are a doctor’s most important duties.

Clinical interests

  • Alcohol
  • Abnormal liver enzymes
  • Fatty liver disease
  • Viral hepatitis
  • General gastroenterology
show more
  • Intensive care management of liver disease patients
  • Autoimmune and Metabolic liver disease
show less

Current posts

  • Clinical Senior Lecturer and Consultant Hepatologist
    University College London and The Royal Free Hospitals

Medical training

Year qualified 1994
  • United Medical and Dental Schools of Guy’s and St Thomas’s Hospitals 1994


100 Days Dry Challenge: Final Orders
Dr O'Brien uses a FibroScan® test to measure the impact of not drinking alcohol for a prolonged period.
This is what happens to your body after all the heavy drinking at Christmas
Dr O'Brien is extensively quoted on the physical drawbacks of drinking alcohol.

Personal interests

Dr O’Brien is a fitness fanatic but most of all enjoys spending time with his wife and two gorgeous children.

Appointment enquiries: +44 (0) 20 3944 1073 Concierge service: +44 (0) 203 219 3323 Self-Pay service: +44 (0) 203 918 7301International office: +44 (0) 203 219 3266 Invoice and payment enquiries: +44 (0) 207 616 7708 General enquiries: +44 (0) 20 3918 9135

Breast services appointments: +44 (0) 207 616 7653 Diagnostics appointments: +44 (0) 207 616 7653 Endoscopy appointments: +44 (0) 207 616 7760 Eye centre appointments: +44 (0) 207 616 7768 Haematology appointments: +44 (0) 207 535 5503 Kidney services appointments: +44 (0) 207 224 5234 Liver services appointments: +44 (0) 207 616 7719 Physiotherapy appointments: +44 (0) 207 616 7651 Radiology appointments: +44 (0) 207 616 7653

Close menu