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The London Clinic


  • Hepatology

Sub specialties

  • Endoscopy
  • Fibroscan

Clinical interests

  • Alcohol
  • Abnormal liver enzymes
  • Fatty liver disease
  • Viral hepatitis
  • General gastroenterology
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  • Intensive care management of liver disease patients
  • Autoimmune and Metabolic liver disease
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Professional profile

Dr Alastair O’Brien is a Clinical Senior Lecturer and Consultant Hepatologist at University College London and The Royal Free Hospitals. His research in infection and liver disease has been published in the most prestigious medical Journals such as The Lancet, Nature Medicine, Hepatology and Gastroenterology.
He currently holds approximately £2million in grant funding from the Wellcome Trust, The Medical Research Council and The Department of Health. He is able to combine clinical excellence with running a laboratory research group and a clinical trial team. He is the chief investigator for ATTIRE which will be the largest interventional study ever performed in patients with acute decompensation of cirrhosis taking place at more than 20 sites over the next three more

He is also the associate editor for the British Medical Journal open Gastroenterology and has written the hepatology chapter for the best-selling medical textbook Kumar and Clarke’s Clinical Medicine, 9th Edition.
Dr O’Brien is a great advocate of patient choice and believes that empathy and listening to people are a doctor’s most important duties.

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Personal profile

Dr O’Brien is a fitness fanatic but most of all enjoys spending time with his wife and two gorgeous children.

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Part of

Dr O'Brien is a member of the London Liver Group



100 Days Dry Challenge: Final Orders
Dr O'Brien uses a FibroScan® test to measure the impact of not drinking alcohol for a prolonged period.

Men's Health April 2018

This is what happens to your body after all the heavy drinking at Christmas
Dr O'Brien is extensively quoted on the physical drawbacks of drinking alcohol.

Cosmopolitan December 2017

Current posts

  • Clinical Senior Lecturer and Consultant Hepatologist
    University College London and The Royal Free Hospitals

Medical training

Year qualified
  • United Medical and Dental Schools of Guy’s and St Thomas’s Hospitals

Ages treated

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Clinic location

116 Harley Street
London W1G 7JL
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Clinic times

Wednesday: 1.30pm - 5pm
Thursday: 1.30 - 5pm


Karen Baxter and Jeanette Brindley
020 7616 7617

Main switchboard: +44 (0) 207 935 4444

Treatment enquiries: +44 (0) 207 616 7693Consultant appointments: +44 (0) 207 616 7693 Prices for self funding patients: +44 (0) 203 219 3315Physiotherapy appointments: +44 (0) 207 616 7651X-ray and scan appointments: +44 (0) 207 616 7653Invoice and payment enquiries: +44 (0) 207 616 7708

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