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General enquiries:
+44 (0)207 935 4444
Book an appointment:
+44 (0)207 616 7693
Self-pay enquiry:
+44 (0)203 219 3315
The London Clinic
Professor Alastair O'Brien is a Consultant Hepatologist at The London Clinic, specialising in liver conditions.

Specialties and sub-specialties

Hepatology
Endoscopy
Fibroscan

Specialist microsite

London Liver Group

Professional profile

Alastair O’Brien is a Professor of Hepatology at University College London and The Royal Free Hospitals. He runs a successful research group focused on infection and immune dysfunction in liver disease.

His work has been published in the most prestigious medical Journals such as The Lancet, The New England Journal of Medicine, Nature Medicine, Hepatology and Gastroenterology.

He currently holds approximately £4m in grant funding from the Wellcome Trust, The Medical Research Council and National Institute for Health Research. He is able to combine clinical excellence with running a laboratory research group and a clinical trial team. 

He is the chief investigator for the ATTIRE trial (Albumin To prevenT Infection in chronic liveR failurE) which recently completed and is the largest trial in advanced liver disease worldwide over the last 5 years. The results will be published in 2020.

His team has just started another large scale trial of antibiotic prophylaxis to prevent infection in patients with cirrhosis.

He is also the associate editor for the British Medical Journal open Gastroenterology and has written the hepatology chapter for the best-selling medical textbook Kumar and Clarke’s Clinical Medicine, 9 and 10th Edition and joint-authored the prize-winning Kumar and Clarke’s Clinical Medicine handbook. 

Dr O’Brien is a great advocate of patient choice and believes that empathy and listening to people are a doctor’s most important duties.

Clinical interests

  • Alcohol
  • Abnormal liver enzymes
  • Fatty liver disease
  • Viral hepatitis
  • General gastroenterology
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  • Intensive care management of liver disease patients
  • Autoimmune and Metabolic liver disease
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Current posts

  • Clinical Senior Lecturer and Consultant Hepatologist
    University College London and The Royal Free Hospitals

Medical training

Year qualified 1994
  • United Medical and Dental Schools of Guy’s and St Thomas’s Hospitals 1994

Articles

100 Days Dry Challenge: Final Orders
Dr O'Brien uses a FibroScan® test to measure the impact of not drinking alcohol for a prolonged period.
This is what happens to your body after all the heavy drinking at Christmas
Dr O'Brien is extensively quoted on the physical drawbacks of drinking alcohol.

Personal interests

Dr O’Brien is a fitness fanatic but most of all enjoys spending time with his wife and two gorgeous children.

Medical Admissions

A nurse with a patient

Facilitating acute admissions into The London Clinic whilst maintaining the highest levels of safety and care, supported by a consultant on-call rota.

Concierge service

Chauffeur loading suitcases into a luxury car

We can support our patients with travel, hotel accommodation, London tours, plus theatre and restaurant reservations.

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Main numbers

General enquiries: 020 7935 4444 Appointments: 020 7616 7693 Self-Pay: 020 3219 3315

Other numbers

Concierge service: 020 3219 3323International office: 020 3 219 3266Invoice and payment enquiries: 020 7616 7708

Your call may be recorded for training and monitoring purposes.

Medical service numbers

Breast services appointments: 020 7616 7653 Diagnostics appointments: 020 7616 7653 Endoscopy appointments: 020 7616 7760 Eye centre appointments: 020 7616 7768 Haematology appointments: 020 7535 5503 Kidney services appointments: 020 7224 5234 Liver services appointments: 020 7616 7719 Physiotherapy appointments: 020 7616 7651 Radiology appointments: 020 7616 7653

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