Date: 15 October 2012

On the 9 January 2012, The London Clinic consultant Mr Dinesh Nathwani successfully performed the world’s first BioPoly partial knee resurfacing procedure. The surgery was conducted through The Advanced Therapies Centre, a newly launched clinical trials facility at The London Clinic, which aims to provide innovative treatment choices for patients through access to trials and novel therapies.

BioPoly knee surgery, which enables the patient to immediately weight bear (with the aid of anti-inflammatories), uses a new type of material combining hyaluronic acid and ultra-high molecular weight polyethylene. When combined, these two materials improve the wear qualities of the prosthesis, whilst also providing a biologically lubricated surface that effectively interacts with the body’s natural tissues. The material is strong enough to take the weight of the body, but also has a degree of flexibility not matched by standard metal replacements.

The procedure is bone conserving, meaning that only the damaged cartilage is removed. The prosthesis is then attached to the end of the bone via a metal stud anchoring it into place. By preserving the healthy bone and cartilage, younger patients experiencing knee problems and who are likely to need further reconstructive work, will have as much healthy bone in-tact as possible, making future operations not only viable, but less complicated.

Patients who will benefit from the BioPoly procedure are those presenting with painful cartilage lesions of the femoral condyle, who might not be suitable candidates for other procedures including biological treatments or joint replacement.

Mary Keal, the first person to receive the BioPoly prosthesis says “My experience of BioPoly so far has been excellent. I was in pain when crossing my legs or walking up stairs; anything where my knee was at an angle. Since my operation, this pain has completely disappeared. I was able to weight bear straight away with the aid of crutches, after 4 weeks I was cycling again, and at 7 weeks I am increasing the resistance.”

Mr Dinesh Nathwani, the Surgeon who performed the operation comments “I am exceptionally pleased with Mary’s progress. The bone conserving nature of the procedure, along with the new BioPoly material used means that recovery has been relatively quick and the original pain experienced has disappeared.”

The London Clinic is one of the four UK centres that are involved in this multi- centre registry trial which has been fully approved by the UK multi regional ethics committee and data collection and analysis of this study is on-going. The London Clinic is committed to utilising its state of the art facilities and world leading expertise, in order to provide patients with access to novel therapies, procedures and the best possible care options.


For more press information, please contact The London Clinic Press Office on 020 7535 5507 or email

Notes to Editors:

The London Clinic

  • The Advanced Therapies Centre offers patients the latest advances in treatments whilst adhering to the strict UK legislation regulating the safe use of unlicensed medication for clinical trials or Named Patient Programs. Information including regulations changes collection, risk assessment and guidelines for use with regular reporting and monitoring
  • The London Clinic is the UK’s largest independently-owned non-profit hospital
  • Over 250 patient beds and 12 operating theatres including dedicated endoscopy suites and a day surgery unit
  • 24 hour consultant-led Intensive Care Unit with 11 beds
  •  As a registered charity and not-for-profit organisation, The London Clinic is able to continuously reinvest in the latest medical technology, facilities and clinical and nursing support
  • Highly complex procedures in addition to routine surgery and medicine such as organ transplants, radiosurgery, radiotherapy, robotic surgery and neurosurgery
  • Located on Harley Street in the heart of London’s medical community
  • Long-standing international reputation attracting leading consultants for nearly 80 years
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